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1

Kinetics of wound-induced v-Ha-ras transgene expression and papilloma development in transgenic Tg.AC mice

Ronald E. Cannon, Judson W. Spalding, Carol S. Trempus, Carl J. Szczesniak, Kelly M. Virgil, Michael C. Humble, Raymond W. Tennant

Journal:

Molecular Carcinogenesis

Year:

1997

Language:

english

File:

PDF, 637 KB

english, 1997

2

Induction of transgene expression in Tg.AC (v-Ha-ras) transgenic mice concomitant with DNA hypomethylation

Ronald E. Cannon, Judson W. Spalding, Kelly M. Virgil, Randall S. Faircloth, Michael C. Humble, Gregory D. Lacks, Raymond W. Tennant

Journal:

Molecular Carcinogenesis

Year:

1998

Language:

english

File:

PDF, 289 KB

english, 1998

3

Hemizygous Tg.AC transgenic mouse as a potential alternative to the two-year mouse carcinogenicity bioassay: evaluation of husbandry and housing factors

Henry E. Holden, Raymond E. Stoll, Judson W. Spalding, Raymond W. Tennant

Journal:

Journal of Applied Toxicology

Year:

1998

Language:

english

File:

PDF, 50 KB

english, 1998

4

Oral administration of dimethylvinyl chloride increases frequency of forestomach papillomas in Tg.AC mice

Ronald E. Cannon, Samantha Graves, Judson W. Spalding, Carol S. Trempus, Raymond W. Tennant

Journal:

Molecular Carcinogenesis

Year:

2000

Language:

english

File:

PDF, 388 KB

english, 2000

5

Measurement of unscheduled DNA synthesis and S-phase synthesis in rodent hepatocytes following in vivo treatment: Testing of 24 compounds

Jon C. Mirsalis, C. Kim Tyson, Karen L. Steinmetz, Erica K. Loh, Carol M. Hamilton, James P. Bakke, Judson W. Spalding

Journal:

Environmental and Molecular Mutagenesis

Year:

1989

Language:

english

File:

PDF, 665 KB

english, 1989

6

Evaluation of the potential of riddelliine to induce unscheduled DNA synthesis, S-phase synthesis, or micronuclei following in vivo treatment with multiple doses

Dr. Jon C. Mirsalis, Karen L. Steinmetz, Dr. William F. Blazak, Judson W. Spalding

Journal:

Environmental and Molecular Mutagenesis

Year:

1993

Language:

english

File:

PDF, 653 KB

english, 1993

7

Comparison of multiple parameters of rodent carcinogenicity and in vitro genetic toxicity

Raymond W. Tennant, Stanley Stasiewicz, Judson W. Spalding

Journal:

Environmental and Molecular Mutagenesis

Year:

1986

Language:

english

File:

PDF, 1.14 MB

english, 1986

8

Evidence that toxic injury is not always associated with induction of chemical carcinogenesis

Raymond W. Tennant, Michael R. Elwell, Judson W. Spalding, Richard A. Griesemer

Journal:

Molecular Carcinogenesis

Year:

1991

Language:

english

File:

PDF, 1.03 MB

english, 1991

9

Cytogenetic analysis of malignant skin tumors induced in chemically treated TG.AC transgenic mice

John E. French, Bisharah L. Libbus, Laura Hansen, Judson Spalding, Raymond R. Tice, Joel Mahler, Raymond W. Tennant

Journal:

Molecular Carcinogenesis

Year:

1994

Language:

english

File:

PDF, 2.56 MB

english, 1994

10

Biological, cellular, and molecular characteristics of an inducible transgenic skin tumor model: a review

Humble, Michael C, Trempus, Carol S, Spalding, Judson W, Cannon, Ronald E, Tennant, Raymond W

Journal:

Year:

2005

Language:

english

File:

PDF, 267 KB

english, 2005

11

O XV B.1 - O XV B.1 Transgenic mouse models as tools to define specific chemical-gene interactions

Raymond Tennant, Judson Spalding, Raymond Tice, Ronald Cannon, John French

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 134 KB

english, 1997

12

Evaluation of transgenic mouse bioassays for identifying carcinogens and noncarcinogens

Raymond W. Tennant, Judson Spalding, John E. French

Journal:

Mutation Research/Reviews in Genetic Toxicology

Year:

1996

Language:

english

File:

PDF, 740 KB

english, 1996

13

Comparative Expression of Novel Vascular Endothelial Growth Factor/Vascular Permeability Factor Transcripts in Skin, Papillomas, and Carcinomas of v-Ha-rasTg.AC Transgenic Mice and FVB/N Mice

Kathleen L. Tober, Ronald E. Cannon, Judson W. Spalding, Tatiana M. Oberyszyn, Michelle L. Parrett, Andrew I. Rackoff, Andrew S. Oberyszyn, Raymond W. Tennant, Fredika M. Robertson

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 1.08 MB

english, 1998

14

Effect of 4-chlorobiphenyl on substrate transport and phospholipid metabolism in mouse L5178Y lymphoma cells

Judson W. Spalding, Elizabeth Ford, Diane Lane

Journal:

Biochemical Pharmacology

Year:

1976

Language:

english

File:

PDF, 684 KB

english, 1976

15

Arsenic Enhancement of Skin Neoplasia by Chronic Stimulation of Growth Factors

Dori R. Germolec, Judson Spalding, Hsin-Su Yu, G.S. Chen, Petia P. Simeonova, Michael C. Humble, Alessandra Bruccoleri, Gary A. Boorman, Julie F. Foley, Takahiko Yoshida, Michael I. Luster

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 1.32 MB

english, 1998

16

Arsenic can mediate skin neoplasia by chronic stimulation of keratinocyte-derived growth factors

Dori R Germolec, Judson Spalding, Gary A Boorman, James L Wilmer, Takahiko Yoshida, Petia P Simeonova, Alessandra Bruccoleri, Fujio Kayama, Kevin Gaido, Raymond Tennant, Florence Burleson, Wumin Dong,

Journal:

Mutation Research/Reviews in Mutation Research

Year:

1997

Language:

english

File:

PDF, 1024 KB

english, 1997

17

Role of keratinocyte-derived cytokines in chemical toxicity

Michael I. Luster, James L. Wilmer, Dori R. Germolec, Judson Spalding, Takahiko Yoshida, Kevin Gaido, Petia P. Simeonova, Florence G. Burleson, Alessandra Bruccoleri

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 539 KB

english, 1995

18

Studies of the toxicity of Alternaria mali

Miriam K. Slifkin, Judson Spalding

Journal:

Toxicology and Applied Pharmacology

Year:

1970

Language:

english

File:

PDF, 3.81 MB

english, 1970

19

Highly repetitive chromosome changes associated with skin tumor development in transgenic mice treated with TPA

Bisharah L. Libbus, John E. French, Judson Spalding, Laura Hansen, Raymond R. Tice, Raymond W. Tennant

Journal:

Cancer Genetics and Cytogenetics

Year:

1993

Language:

english

File:

PDF, 122 KB

english, 1993

20

Topical and oral administration of the natural water-soluble antioxidant from spinach reduces the multiplicity of papillomas in the Tg.AC mouse model

Abraham Nyska, Liat Lomnitski, Judson Spalding, David B Dunson, Thomas L Goldsworthy, Shlomo Grossman, Margalit Bergman, Gary Boorman

Journal:

Toxicology Letters

Year:

2001

Language:

english

File:

PDF, 155 KB

english, 2001

21

Erratum to “Topical and oral administration of the natural water-soluble antioxidant from spinach reduces the multiplicity of papillomas in the Tg.AC mouse model”: [Toxicol. Lett. 122 (2001) 33–44]

Abraham Nyska, Liat Lomnitski, Judson Spalding, David B. Dunson, Thomas L. Goldsworthy, V. Ben-Shaul, Shlomo Grossman, Margalit Bergman, Gary Boorman

Journal:

Toxicology Letters

Year:

2001

Language:

english

File:

PDF, 37 KB

english, 2001

22

The transgenic Tg.AC mouse model for identification of chemical carcinogens

Raymond W Tennant, Raymond R Tice, Judson W Spalding

Journal:

Toxicology Letters

Year:

1998

Language:

english

File:

PDF, 80 KB

english, 1998

23

Amino acid-activating enzyme levels in different growth states of HeLa cells

Spalding, Judson W., Mueller, Gerald C.

Journal:

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects

Year:

1962

Language:

english

File:

PDF, 458 KB

english, 1962

24

The Metabolism of Basic Proteins in Hela Cell Nuclei

Judson Spalding, Kazuto Kajiwara and Gerald C. Mueller

Journal:

Proceedings of the National Academy of Sciences

Year:

1966

Language:

english

File:

PDF, 1.15 MB

english, 1966

25

Comparative Evaluation of Genetic Toxicity Patterns of Carcinogens and Noncarcinogens: Strategies for Predictive Use of Short-Term Assays

Raymond W. Tennant, Judson W. Spalding, Stanley Stasiewicz, William D. Caspary, James M. Mason and Michael A. Resnick

Journal:

Environmental Health Perspectives

Year:

1987

Language:

english

File:

PDF, 1.89 MB

english, 1987

26

Identifying Chemical Carcinogens and Assessing Potential Risk in Short-Term Bioassays Using Transgenic Mouse Models

Raymond W. Tennant, John E. French and Judson W. Spalding

Journal:

Environmental Health Perspectives

Year:

1995

Language:

english

File:

PDF, 2.46 MB

english, 1995

27

Supplement 5 || Predictions for the Outcome of Rodent Carcinogenicity Bioassays: Identification of Trans-Species Carcinogens and Noncarcinogens

Raymond W. Tennant and Judson Spalding

Journal:

Environmental Health Perspectives

Year:

1996

Language:

english

File:

PDF, 264 KB

english, 1996

28

Mechanism of Skin Tumorigenesis by Contact Sensitizers: The Effect of the Corticosteroid Fluocinolone Acetonide on Inflammation and Tumor Induction by 2,4 Dinitro-1-Fluorobenzene in the Skin of the TG.AC (v-Ha-ras) Mouse

Roy E. Albert, John E. French, Robert Maronpot, Judson Spalding and Raymond Tennant

Journal:

Environmental Health Perspectives

Year:

1996

Language:

english

File:

PDF, 1.40 MB

english, 1996

29

Supplement 2: Impact of the Environment on Reproductive Health || Transformation of BALB/c-3T3 Cells: V. Transformation Responses of 168 Chemicals Compared with Mutagenicity in Salmonella and Carcinogenicity in Rodent Bioassays

Edwin J. Matthews, Judson W. Spalding and Raymond W. Tennant

Journal:

Environmental Health Perspectives

Year:

1993

Language:

english

File:

PDF, 16.79 MB

english, 1993

30

Supplement 2: Impact of the Environment on Reproductive Health || Transformation of BALB/c-3T3 Cells: IV. Rank-Ordered Potency of 24 Chemical Responses Detected in a Sensitive New Assay Procedure

Edwin J. Matthews, Judson W. Spalding and Raymond W. Tennant

Journal:

Environmental Health Perspectives

Year:

1993

Language:

english

File:

PDF, 4.47 MB

english, 1993

31

Predicting Chemical Carcinogenesis in Rodents

Joseph T. Wachsman, Douglas W. Bristol, Judson Spalding, Michael Shelby and Raymond W. Tennant

Journal:

Environmental Health Perspectives

Year:

1993

Language:

english

File:

PDF, 527 KB

english, 1993

32

Isolation and Characterization of Rabbit Lung Lamellar Bodies

Spalding, Judson W., Ortner, Mary J., Tombropoulos, Elias G., Gilmore, Linda B., Hook, Gary E.R.

Journal:

Experimental Lung Research

Year:

1983

Language:

english

File:

PDF, 1.40 MB

english, 1983

33

The Tg.AC (v-Ha-ras) Transgenic Mouse: Nature of the Model

Tennant, Raymond, Stasiewicz, Stanley, Eastin, William, Mennear, John, Spalding, Judson

Journal:

Toxicologic Pathology

Year:

2001

Language:

english

File:

PDF, 165 KB

english, 2001

34

Chemically induced skin carcinogenesis in a transgenic mouse line (TG·AC) carrying a v-Ha- ras gene

Spalding, Judson W., Momma, Junko, Elwell, Michael R., Tennant, Raymond W.

Journal:

Year:

1993

Language:

english

File:

PDF, 744 KB

english, 1993

35

Tg.AC Genetically Altered Mouse: Assay Working Group Overview of Available Data

Eastin, William, Mennear, John, Tennant, Ray, Stoll, Ray, Branstetter, Dan, Bucher, John, McCullough, Bruce, Binder, Robert, Spalding, Judson, Mahler, Joel

Journal:

Toxicologic Pathology

Year:

2001

Language:

english

File:

PDF, 384 KB

english, 2001

36

THE USE OF TRANSGENIC ANIMALS IN CANCER TESTING

John E. French, Judson W. Spalding,,

Journal:

Inhalation Toxicology

Year:

1999

Language:

english

File:

PDF, 55 KB

english, 1999

37

Induction of hepatic cell proliferation and unscheduled DNA synthesis in mouse hepatocytes following in vivo treatment

Mirsalis, Jon C., Tyson, C. Kimerly, Loh, Erica N., Steinmetz, Karen L., Bakke, James P., Hamilton, Carol M., Spak, Dana K., Spalding, Judson W.

Journal:

Year:

1985

Language:

english

File:

PDF, 312 KB

english, 1985

38

Prediction of the outcome of rodent carcinogenicity bioassays currently being conducted on 44 chemicals by the National Toxicology Program

Tennant, Raymond W., Spalding, Judson, Stasiewicz, Stanley, Ashby, John

Journal:

Year:

1990

Language:

english

File:

PDF, 790 KB

english, 1990

39

Gene manipulation and genetic toxicology

Tennant, Raymond W., Hansen, Laura, Spalding, Judson

Journal:

Year:

1994

Language:

english

File:

PDF, 460 KB

english, 1994